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Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Conjunctival biopsies and ophthalmic lesions: A histopathologic study in eastern India
Santosh K Mondal1, Dipanwita R Nag, Ranjana Bandyopadhyay
1Department of Pathology, Medical College, Kolkata, India.
Background:
The conjunctiva is a thin and flexible mucus membrane that provides a protective barrier to the eye. Very few histopathologic studies have been conducted on conjunctival biopsies in eastern India.
Materials And Methods:
120 conjunctival biopsies from 117 patients (76 males, 41 females) received during 8 years (January 2003-December 2010) were included in this study.
Results:
HISTOLOGIC DIAGNOSES WERE: degenerative lesions in 38 cases (31.66%), benign epithelial lesions in 23 cases (19.16%), premalignant and malignant epithelial lesions in 27 cases (22.5%), melanocytic lesions in 10 cases (8.33%), lymphoid in 7 cases (5.83%), and miscellaneous in 15 cases (12.5%).
Conclusion:
Squamous papilloma was the commonest benign tumor, whereas the commonest malignant tumor was squamous cell carcinoma. Melanocytic lesions were less prevalent compared to other/western studies.

