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Related Concept Videos

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

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Related Experiment Video

Updated: May 9, 2026

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
07:05

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation

Published on: December 15, 2017

Molecular imaging in gastroenterology.

Raja Atreya1, Martin Goetz

  • 1Medizinische Klinik 1, Universitätsklinikum Erlangen, Ulmenweg 18, D-91054 Erlangen, Germany.

Nature Reviews. Gastroenterology & Hepatology
|July 17, 2013
PubMed
Summary

Molecular imaging uses fluorescent probes to detect cancerous lesions in the gastrointestinal tract. This technique aids in personalized cancer treatment and improves endoscopic diagnosis.

Area of Science:

  • Gastroenterology
  • Oncology
  • Medical Imaging

Background:

  • Molecular imaging is emerging in gastroenterology for enhanced endoscopic diagnosis.
  • It aligns with advancements in targeted therapies and endoscopy technology.
  • The goal is to improve detection and characterization of gastrointestinal neoplastic lesions.

Purpose of the Study:

  • To review the applications of molecular imaging in gastrointestinal endoscopy.
  • To highlight techniques with potential for translational science and clinical practice.

Main Methods:

  • Utilizes fluorescently labeled probes targeting specific molecular signatures of neoplastic lesions.
  • Employs various exogenous molecular probes, including antibodies, oligopeptides, affibodies, aptamers, and activatable probes.

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Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
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Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

Related Experiment Videos

Last Updated: May 9, 2026

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
07:05

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation

Published on: December 15, 2017

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

  • Evaluates molecular imaging in wide-field imaging for lesion detection and microscopic analysis for in vivo tumor characterization.

    • Main Results:

    • Molecular imaging shows promise as a 'red flag' technique for improved lesion detection.
    • In vivo characterization of tumor molecular fingerprints can assess response to targeted therapy.
    • Several molecular imaging applications are nearing clinical transition.

    Conclusions:

    • Molecular imaging offers significant potential to advance gastrointestinal oncology.
    • It facilitates individualized treatment strategies by enabling precise diagnosis and therapy response assessment.
    • The review focuses on applications with immediate translational or clinical relevance in endoscopy.