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Updated: Aug 5, 2026

HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells
Published on: July 20, 2016
[Changes in redox potentials in serum samples as affected by adenosine triphosphate]
1Abteilung für Nuklearmedizin, Bereich Medizin der Wilhelm-Pieck-Universität Rostock.
Abstract:
Irradiated serum samples show characteristic alterations of their redoxpotential. This reaction is in close correlation to metabolic alterations, that for instance occur with tumor growth or severe inflammatory diseases. The role of ATP as universal biochemical energy transmitter led us to study the influence of ATP on redoxpotential in serum. In result the sole addition of ATP to serum in vitro gave a clear alteration of the redoxpotentials. In healthy persons a shifting of redoxpotentials was seen to high positive values. On the other hand ATP has slight influence on sera of tumor patients.
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