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Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease
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Prospective memory deficits in euthymic bipolar disorder patients: a preliminary study.

Jing-Jing Zhou1, Yu-Tao Xiang, Chuan-Yue Wang

  • 1Department of Psychiatry, Beijing Anding Hospital, Capital Medical University, Beijing, China.

Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists
|July 17, 2013
PubMed
Summary

Bipolar disorder (BD) patients in remission show prospective memory deficits, particularly in time-based tasks. These impairments may represent a persistent trait of the condition, impacting daily functioning.

Keywords:
bipolar disordereuthymiaintelligenceprospective memoryretrospective memory

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Prospective memory (PM) involves remembering future intentions.
  • PM deficits in euthymic bipolar disorder (BD) are understudied.
  • This research investigates PM nature and correlates in remitted BD patients.

Purpose of the Study:

  • To assess prospective memory performance in euthymic BD patients.
  • To identify factors associated with prospective memory deficits in BD.
  • To determine if PM impairment is a trait characteristic of BD.

Main Methods:

  • 47 euthymic BD patients and 47 controls completed assessments.
  • Evaluated prospective memory (CAMPROMPT), retrospective memory (WMS-R), IQ (Raven's), and executive function (WCST).
  • BD symptom severity was rated using HDRS and YMRS.

Main Results:

  • Euthymic BD patients exhibited significantly poorer time-based prospective memory than controls.
  • Lower IQ (Raven's) correlated with poorer time-based PM in BD patients.
  • Lower retrospective memory (WMS-R) correlated with poorer event-based PM in BD patients.

Conclusions:

  • Prospective memory deficits are evident in euthymic BD patients.
  • These findings suggest prospective memory impairment is a trait deficit in BD.
  • Impaired prospective memory may persist even during remission in bipolar disorder.