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Morvan syndrome: after scrotal sac drainage and chemical instillation in hydrocele
Sanjay Sharma1, Pranita Sharma
1Department of Neurology, Ramkrishna Care Hospital, Raipur, Chhattisgarh, India. drsanjaysharma123@rediffmail.com
Abstract:
We have described the occurrence of Morvan syndrome (MoS) after scrotal tap and injection of sclerosing agent for the treatment of hydrocele in 5 male. The mean age was 43.2 years, and the gap between the procedure and development of clinical features suggestive of MoS was 1.5-3 months. The neurophysiology studies demonstrated hyper excitability of peripheral nerves. In addition, autonomic dysfunction, severe insomnia, and neuropsychiatric features were observed. Significant VGKC-complex/CASPR-2 antibodies titer were present in all cases. Symptoms resolved spontaneously within 6 months of onset.
Insights
Morvan syndrome (MoS) can occur after hydrocele treatment. This neurological condition, characterized by nerve hyperexcitability and neuropsychiatric symptoms, resolved spontaneously in all five male patients within six months.
Area of Science:
- Neurology
- Immunology
Background:
- Hydrocele is a common condition often treated with scrotal tap and sclerosing agents.
- Morvan syndrome (MoS) is a rare autoimmune disorder affecting the peripheral nervous system and central nervous system.
Observation:
- Five male patients developed MoS following hydrocele treatment.
- Clinical manifestations appeared 1.5-3 months post-procedure.
- Patients exhibited peripheral nerve hyperexcitability, autonomic dysfunction, severe insomnia, and neuropsychiatric symptoms.
Findings:
- All patients presented with significant VGKC-complex/CASPR-2 antibody titers.
- Neurophysiological studies confirmed peripheral nerve hyperexcitability.
- Symptoms showed spontaneous resolution within six months.
Implications:
- This suggests a potential link between hydrocele treatment and MoS development.
- Early identification and monitoring of neurological symptoms post-procedure are crucial.
- The findings contribute to understanding MoS pathogenesis and its association with specific medical interventions.
