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Development of a DNA sensor using a molecular logic gate

D Bhattacharjee1, Dibyendu Dey, S Chakraborty

  • 1Thin Film and Nanoscience Laboratory, Department of Physics, Tripura University, Suryamaninagar, 799022, Tripura, India.

Journal of Biological Physics
|July 18, 2013
PubMed

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...