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Updated: May 9, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Percutaneous edge-to-edge mitral valve repair. Current clinical evidence with the MitraClip System
R Estevez-Loureiro1, O Franzen
1Department of Cardiology, Rigshospitalet Copenhagen, Blegdamsvej 9, Copenhagen, Denmark.
Abstract:
In the past few years, a myriad of technologies have been developed for percutaneous repair of the mitral valve for patients with severe mitral regurgitation (MR) and at high risk for traditional open-heart mitral valve surgery. Among them, MitraClip has emerged as the only clinically safe and effective method for percutaneous mitral valve repair. This device mimics the surgical edge-to-edge mitral valve repair initially described by Dr. Alfieri. In this article, we review the current clinical evidence on the use of the MitraClip--from the randomized control trial EVEREST II to the information derived from expert high-volume centers.
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