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Updated: May 9, 2026

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
Published on: April 14, 2016
Gelatinous bone marrow transformation secondary to unusual eating habits and drastic weight loss
Rafiullah1, Rezwan Islam, Ruth Mahmood
1Department of Internal Medicine, Ministry Saint Clare's Hospital, Weston, Wisconsin, USA. drrafiullahkhan@yahoo.com
Abstract:
Gelatinous bone marrow transformation (GMT), also known as starvation bone marrow, has been reported in a number of chronic illnesses, eating disorders (anorexia nervosa) and malignancies. We report the case of a 37-year-old man with a history of bipolar disorder and obesity (weighing >300 pounds) who presented due to recently developing a deep yellow colour to his skin. Over the past 2 years, through diet and exercise, he lost over 150 pounds. He reported running 6-8 miles per day and eating 'lots of squash'. We made the diagnosis of starvation hepatitis and bone marrow degeneration, and referred the patient to a dietician and haematologist/oncologist, where improvements were observed at 4 weeks follow-up.
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