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Updated: May 9, 2026

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
Published on: November 20, 2016
Non-arteritic anterior ischemic optic neuropathy secondary to acute primary-angle closure
1Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA.
Purpose:
To describe a case of non-arteritic ischemic optic neuropathy (NAION) secondary to acute primary-angle closure (APAC).
Methods:
Case report.
Results:
A 50-year-old woman with painful visual loss in the right eye was found to be in APAC with a right afferent pupillary defect. Laser peripheral iridotomy relieved pain but did not improve vision. Diffuse optic disc edema in the right eye and a small cup-to-disc ratio in the left eye were evident. Magnetic resonance imaging was normal. The patient was diagnosed with non-arteritic ischemic optic neuropathy (NAION) secondary to APAC, a rare clinical entity which can result in markedly decreased visual acuity.
Conclusion:
NAION secondary to APAC is a rare clinical entity that can result in severe vision loss.
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