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Updated: May 9, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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Published on: February 21, 2018

Developmental differences in IFN signaling affect GATA1s-induced megakaryocyte hyperproliferation

Andrew J Woo, Karen Wieland, Hui Huang

    The Journal of Clinical Investigation
    |July 19, 2013
    PubMed
    Summary

    Type I interferon signaling explains why Down syndrome-related blood disorders resolve in infants. This pathway suppresses abnormal cell growth in fetal liver, preventing leukemia development.

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