Related Experiment Video
Updated: May 9, 2026

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
[Delay in the introduction of treatment modalities for neuroendocrine tumors in Japan]
1Kansai Electric Power Hospital, Endocrine Tumor Center, Osaka, Japan.
Abstract:
The incidence of pancreatic-intestinal neuroendocrine tumors is rapidly increasing worldwide, and intensive research has been carried out for the standardization of its treatment. In Japan, a few diagnostic and treatment modalities including somatostatin receptor scintigraphy(SRS)have not been approved by the government. Therefore, we intend to improve this situation as soon as possible.
Insights
The global incidence of pancreatic-intestinal neuroendocrine tumors is rising, necessitating standardized treatments. In Japan, key diagnostic tools like somatostatin receptor scintigraphy (SRS) lack government approval, hindering optimal patient care.
Area of Science:
- Oncology
- Nuclear Medicine
- Gastroenterology
Context:
- Pancreatic-intestinal neuroendocrine tumors (NETs) represent a growing global health concern.
- Standardization of diagnostic and treatment protocols for NETs is an ongoing challenge.
- Specific diagnostic modalities, such as somatostatin receptor scintigraphy (SRS), face regulatory hurdles in Japan.
Purpose:
- To address the unmet need for approved diagnostic and treatment modalities for pancreatic-intestinal neuroendocrine tumors in Japan.
- To advocate for the integration of advanced imaging techniques like SRS into routine clinical practice.
- To improve the management and outcomes for patients with neuroendocrine tumors in Japan.
Summary:
- The incidence of pancreatic-intestinal neuroendocrine tumors (NETs) is increasing worldwide.
- Intensive research focuses on standardizing NET treatment protocols.
- Key diagnostic tools, including somatostatin receptor scintigraphy (SRS), are not government-approved in Japan, creating a treatment gap.
Impact:
- This initiative aims to expedite the approval of essential diagnostic and treatment tools for NETs in Japan.
- Improved access to modalities like SRS will enhance diagnostic accuracy and treatment planning.
- Ultimately, this will lead to better patient care and outcomes for individuals with neuroendocrine tumors in Japan.
Related Concept Videos
Treatment Resistant Cancers
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Drug Administration and Therapy Phases: Overview
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...
Cushing Syndrome I: Introduction
