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Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice
Published on: October 27, 2014
[Comparison of a safety evaluation between paclitaxel injection NK and Taxol®]
Daigo Yamamoto1, Yu Tsubota, Noriko Sueoka
1Dept. of Surgery, Kansai Medical University.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|July 19, 2013
Abstract:
Paclitaxel injection NK(NK)is a generic product containing the same amount of ingredients as a Taxol®Injection. We examined the safety of NK in clinical practice compared to the original drug. Our results suggested that for the cancer patient, most safety profiles between NK and the original drug are similar. However, patients who received Taxol®Injection had significantly more grade 2 neuropathy compared to those who received NK(p<0. 01).
