Vector decoys trick the immune response
Thierry VandenDriessche1, Marinee K Chuah
1Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, Brussels, Belgium. thierry.vandendriessche@vub.ac.be
Abstract:
Humoral immunity to adeno-associated viral vectors can be overcome by using empty capsid mutant "decoys" for preexisting antibodies (Mingozzi et al., this issue).
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