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Updated: May 9, 2026

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
Published on: June 17, 2022
Developing and testing theory-based and evidence-based interventions to promote switching to arsenic-safe wells in
Jennifer Inauen1, Hans-Joachim Mosler2
1Eawag: Swiss Federal Institute of Aquatic Science & Technology, Switzerland University of Konstanz, Germany jennifer.inauen@uni-konstanz.de.
Abstract:
Millions of people in Bangladesh drink arsenic-contaminated water despite increased awareness of consequences to health. Theory-based and evidence-based interventions are likely to have greater impact on people switching to existing arsenic-safe wells than providing information alone. To test this assumption, we first developed interventions based on an empirical test of the Risk, Attitudes, Norms, Abilities and Self-regulation (RANAS) model of behaviour change. In the second part of this study, a cluster-randomised controlled trial revealed that in accordance with our hypotheses, information alone showed smaller increases in switching to arsenic-safe wells than information with reminders or information with reminders and implementation intentions.
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