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Related Concept Videos

Lateralization01:28

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Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
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Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
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Published on: March 21, 2025

Apraxia in left-handers.

Georg Goldenberg1

  • 1Department of Neuropsychology, Bogenhausen Hospital, Munich, Germany. Georg.Goldenberg@extern.lrz-muenchen.de

Brain : a Journal of Neurology
|July 19, 2013
PubMed
Summary
This summary is machine-generated.

Apraxia and aphasia associations differ in left-handed individuals due to brain hemisphere lateralization. This study disentangles apraxia

Keywords:
apraxiahandednessimitationpantomimespatial processingtool use

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Area of Science:

  • Neuroscience
  • Cognitive Neurology
  • Clinical Neuropsychology

Background:

  • In right-handed individuals, apraxia and aphasia typically result from left hemisphere damage, which also controls the dominant right hand.
  • Left-handed individuals can exhibit dissociation between language lateralization and control of the dominant hand, allowing for clearer distinctions between apraxia, aphasia, and handedness.

Purpose of the Study:

  • To investigate the relationship between apraxia, aphasia, and handedness in left-handed patients with unilateral brain lesions.
  • To disentangle the association of apraxia with aphasia from its association with handedness in left-handed individuals.

Main Methods:

  • Examined pantomime of tool use, actual tool use, and imitation of meaningless hand and finger postures in 50 left-handed subjects with unilateral hemisphere lesions.
  • Assessed for dissociations between apraxia, aphasia, and handedness across different tasks.

Main Results:

  • Observed dissociations of apraxia from both handedness and aphasia in left-handed patients.
  • Defective imitation of hand postures (but not finger postures) was more frequent after right than left brain damage, particularly in patients with hemi-neglect.
  • Impairment in pantomime of tool use was milder in left-handed apraxic patients compared to right-handed apraxic patients, correlating with milder aphasia severity.

Conclusions:

  • The association of right hemisphere damage with apraxia may relate to spatial processing rather than dominant hand control.
  • Left-handedness can alleviate the severity of both apraxia and aphasia compared to right-handed individuals.
  • Findings highlight the complex interplay between brain lateralization, handedness, and the manifestation of neurological deficits like apraxia and aphasia.