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[Hip joint endoprosthesis and metal sensitivity. Studies using the leukocyte migration test]
H Grasshoff1, D Schmidt, K Kluge
1Klinik für Orthopädie, Medizinischen Akademie, Magdeburg.
Beitrage Zur Orthopadie Und Traumatologie
|April 1, 1990
Summary
The Leukocyte Migration Test (LMT) detects metal sensitivity. This study found no link between metal sensitivity and artificial hip joint loosening in patients with coxarthrosis or hip replacements.
Area of Science:
- Immunology
- Orthopedic Surgery
- Toxicology
Context:
- Metal sensitivity is a concern in patients with orthopedic implants.
- The Leukocyte Migration Test (LMT) is a diagnostic tool for metal hypersensitivity.
- Coxarthrosis and total hip replacement patients are at risk for metal exposure.
Purpose:
- To investigate the sensitivity of the Leukocyte Migration Test (LMT) for detecting metal sensitivity.
- To determine if there is a difference in chromium, cobalt, and nickel sensitivity between patients with coxarthrosis and those with total hip replacements.
- To assess the relationship between metal sensitivity and the loosening of artificial hip joints.
Summary:
- The Leukocyte Migration Test (LMT) demonstrated sensitivity in detecting metal sensitivity.
- No significant differences in chromium, cobalt, or nickel sensitivity were observed between the coxarthrosis and total hip replacement groups.
- The study found no correlation between diagnosed metal sensitivity and the loosening of artificial hip joints in either patient cohort.
Impact:
- This research clarifies the role of metal sensitivity in orthopedic implant outcomes.
- Findings suggest that metal sensitivity, as detected by LMT, may not be a primary factor in artificial hip joint loosening.
- Provides valuable data for clinicians managing patients with metal sensitivity and orthopedic implants.