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Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...

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Updated: May 9, 2026

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
16:56

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections

Published on: August 30, 2014

Vaccines against Coccidioides.

Hee Jung Yoon1, Karl V Clemons

  • 1Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital, Daejeon, Korea. yhj822@medimail.co.kr

The Korean Journal of Internal Medicine
|July 19, 2013
PubMed
Summary
This summary is machine-generated.

Developing fungal vaccines for coccidioidomycosis is crucial for modern medicine. These vaccines should prevent disease by targeting virulence factors, reducing reliance on antibiotics and minimizing resistance.

Keywords:
CoccidioidomycosisFungal vaccines

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Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

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Last Updated: May 9, 2026

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
16:56

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections

Published on: August 30, 2014

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
09:57

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens

Published on: February 14, 2011

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

Area of Science:

  • Medical Mycology
  • Vaccinology
  • Infectious Diseases

Background:

  • Fungal infections pose a growing threat in medicine.
  • Chemotherapy for fungal diseases contributes to antibiotic resistance.
  • Effective vaccines are needed to combat fungal pathogens.

Purpose of the Study:

  • To review the developmental status of vaccines against coccidioidomycosis.
  • To highlight the need for novel vaccine strategies.
  • To discuss vaccine targets that prevent disease without eradicating the fungus.

Main Methods:

  • Literature review of current research on coccidioidomycosis vaccines.
  • Analysis of immunological approaches for fungal disease prevention.
  • Evaluation of virulence factors as potential vaccine targets.

Main Results:

  • Current research focuses on vaccines for coccidioidomycosis.
  • Vaccine development aims to integrate with or replace chemotherapy.
  • Targeting low-penetrance virulence traits is a key strategy.

Conclusions:

  • Vaccines against coccidioidomycosis are under development.
  • A successful vaccine should prevent disease by neutralizing specific fungal traits.
  • Minimizing antibiotic use and resistance is a critical goal for fungal vaccine development.