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Updated: May 9, 2026

A New Hybrid Quantitative Evaluation Model for Axillary Junctional Hemorrhage in Swine
Published on: December 6, 2024
Understanding jejunal hemorrhage syndrome
Mohamed M Elhanafy1, Dennis D French, Ueli Braun
1Rural Animal Health Management Service, Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA. elhanafy@illinois.edu
Jejunal hemorrhage syndrome (JHS) in dairy cattle is a fatal enterotoxemic disorder often linked to Clostridium perfringens type A and Aspergillus fumigatus. Early lactation, high-energy diets may increase risk, with limited treatment success.
Area of Science:
- Veterinary Medicine
- Ruminant Health
- Bovine Diseases
Background:
- Jejunal hemorrhage syndrome (JHS) is an acute, fatal enterotoxemic disorder in dairy cattle.
- JHS has been increasingly reported in recent decades, particularly in early lactation.
- A strong association exists between JHS and Clostridium perfringens type A infection, with Aspergillus fumigatus also implicated.
Purpose of the Study:
- To review the potential etiologic and risk factors for Jejunal Hemorrhage Syndrome (JHS) in dairy cattle.
- To describe the clinical signs, diagnostic approaches, and treatment outcomes for JHS.
- To highlight the challenges in preventing and managing this severe bovine disease.
Main Methods:
- Literature review of studies on Jejunal Hemorrhage Syndrome (JHS).
- Analysis of associations between JHS and potential causative agents like Clostridium perfringens type A and Aspergillus fumigatus.
- Compilation of information on clinical presentation, diagnostic tests, and treatment strategies.
Main Results:
- JHS is strongly associated with Clostridium perfringens type A and potentially Aspergillus fumigatus.
- Clinical signs include decreased feed intake, rapid condition loss, abdominal distension, and bloody feces, often occurring during early lactation on high-energy, low-fiber diets.
- Preventive strategies are undetermined, and intensive medical or surgical treatments have limited success.
Conclusions:
- Jejunal Hemorrhage Syndrome (JHS) poses a significant threat to dairy cattle health due to its high fatality and lack of effective prevention.
- Current understanding suggests a multifactorial etiology involving infectious agents and dietary factors.
- Further research is needed to develop effective preventative measures and treatments for JHS.
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