Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 9, 2026

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
09:54

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

Published on: August 20, 2018

Dendrimers in layer-by-layer assemblies: synthesis and applications.

Katsuhiko Sato1, Jun-ichi Anzai

  • 1Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578, Japan.

Molecules (Basel, Switzerland)
|July 23, 2013
PubMed
Summary

Dendrimer-containing layer-by-layer assemblies offer versatile applications in biosensing, drug delivery, and bio-imaging. These advanced materials enable high-performance sensors and targeted therapies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Shrinkage paradox in intraductal papillary mucinous neoplasms is associated with higher concomitant pancreatic cancer risk.

European radiology·2026
Same author

Optimal Stenting Strategy During Chemotherapy: Impact of Time to First Reintervention on Survival in Malignant Hilar Biliary Obstruction.

DEN open·2026
Same author

Endoscopic retrieval of an N-butyl-2-cyanoacrylate cast from the common bile duct: a rare complication of portal vein embolization.

Endoscopy·2026
Same author

Activation of the Integrin αV-YAP-CTGF Axis in Liver Sinusoidal Endothelial Cells Promotes Liver Fibrogenesis, Leading to Portal Hypertension and Liver Carcinogenesis in Congestive Hepatopathy.

Gastroenterology·2026
Same author

Geometrical preference of anchoring sites in the unicellular organism <i>Stentor coeruleus</i>.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Full-Coverage Drug-Eluting Stent Vs Drug-Coated Balloon in De Novo Femoropopliteal Lesions: Three-Year TASC II-Stratified Outcomes.

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists·2026

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Layer-by-layer (LbL) assembly is a versatile technique for fabricating multilayered thin films and microstructures.
  • Dendrimers, highly branched macromolecules, offer unique properties for advanced material design.
  • Combining dendrimers with LbL assembly creates novel materials with tailored functionalities.

Purpose of the Study:

  • To review the synthesis of dendrimer-containing LbL assemblies.
  • To explore the diverse applications of these assemblies in biosensing, drug delivery, and bio-imaging.
  • To highlight the mechanisms enabling the integration of dendrimers into LbL structures.

Main Methods:

  • Alternating deposition of dendrimers and counter polymers onto substrates.

More Related Videos

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

Layer-by-layer Synthesis and Transfer of Freestanding Conjugated Microporous Polymer Nanomembranes
09:09

Layer-by-layer Synthesis and Transfer of Freestanding Conjugated Microporous Polymer Nanomembranes

Published on: December 15, 2015

Related Experiment Videos

Last Updated: May 9, 2026

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
09:54

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

Published on: August 20, 2018

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

Layer-by-layer Synthesis and Transfer of Freestanding Conjugated Microporous Polymer Nanomembranes
09:09

Layer-by-layer Synthesis and Transfer of Freestanding Conjugated Microporous Polymer Nanomembranes

Published on: December 15, 2015

  • Utilizing various bonding strategies: electrostatic, hydrogen bonding, covalent, and biological affinity.
  • Incorporating functional components like electron transfer mediators and nanoparticles within the assemblies.

    • Main Results:

    • Successful fabrication of dendrimer-containing LbL films and microcapsules.
    • Demonstrated utility in constructing high-performance biosensors through enzyme immobilization.
    • Effective application in controlled drug delivery systems via inclusion complexes or covalent drug modification.
    • Potential for bio-imaging, exemplified by iron oxide nanoparticle-coated LbL films for cancer cell MRI.

    Conclusions:

    • Dendrimer-containing LbL assemblies represent a powerful platform for advanced functional materials.
    • These assemblies show significant promise for developing sophisticated biosensors, targeted drug delivery systems, and innovative bio-imaging agents.
    • The tunable nature of dendrimer-LbL interactions facilitates the creation of materials for diverse biomedical applications.