Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Prosopagnosia01:24

Prosopagnosia

Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

THRIVE: A Phase 3, Randomized, Double-Masked, Placebo-Controlled Study of Veligrotug for Active Thyroid Eye Disease.

Ophthalmology·2026
Same author

The face inversion effect and its influence on intraoperative evaluation during ptosis surgery: results of a survey of Canadian oculoplastic surgeons.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same author

Ecchordosis physaliphora presenting with cerebrospinal fluid leak and meningitis: illustrative case.

Journal of neurosurgery. Case lessons·2026
Same author

A Case of External Beam Radiation Therapy Induced Corneal Damage in the Treatment of Squamoid Eccrine Ductal Carcinoma.

Advances in radiation oncology·2026
Same author

Impact of removal of the lateral orbital rim on intraorbital pressure during endoscopic trans-orbital approach (ETOA): a cadaveric study.

Acta neurochirurgica·2025
Same author

A Challenging Case of Progressive Bilateral Optic Neuropathy.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2025
Same journal

Discoverability of Pediatric Ophthalmologists Among Online Resources.

JAMA ophthalmology·2026
Same journal

Translating AI Into the Eye Clinic-From Models to Clinical Workflow.

JAMA ophthalmology·2026
Same journal

Diagnostic Performance of Prespecified OCT Rules for Glaucomatous Optic Neuropathy in Nonpathologic Myopia.

JAMA ophthalmology·2026
Same journal

Painless Blindness With Conflicting Clues.

JAMA ophthalmology·2026
Same journal

Promise and Pitfalls of Artificial Intelligence Smart Glasses in Low Vision Care.

JAMA ophthalmology·2026
Same journal

Diabetic Retinal Disease Beginning in Childhood.

JAMA ophthalmology·2026
See all related articles

Related Experiment Video

Updated: May 9, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Periocular necrotizing fasciitis causing blindness.

David R Shield1, Javier Servat, Sean Paul

  • 1Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut.

JAMA Ophthalmology
|July 23, 2013
PubMed
Summary
This summary is machine-generated.

Periocular necrotizing fasciitis is a severe infection that can lead to significant vision loss. Early recognition and treatment are crucial for better outcomes in this rare but dangerous condition.

More Related Videos

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats
06:30

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats

Published on: May 23, 2025

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells
13:12

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells

Published on: October 15, 2017

Related Experiment Videos

Last Updated: May 9, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats
06:30

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats

Published on: May 23, 2025

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells
13:12

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells

Published on: October 15, 2017

Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Periocular necrotizing fasciitis is a rare, aggressive soft tissue infection.
  • It carries substantial risks of morbidity and mortality, particularly affecting vision.

Observation:

  • This report details 5 cases of periocular necrotizing fasciitis.
  • All cases resulted in severe vision loss; 3 required orbital exenteration.
  • Causative agents included Group A Streptococcus, MRSA, and Streptococcus anginosus constellatus.

Findings:

  • Periocular necrotizing fasciitis frequently causes severe visual impairment.
  • Streptococcus anginosus constellatus is identified as a novel cause of this condition.

Implications:

  • Clinicians must maintain a high index of suspicion for necrotizing fasciitis.
  • Prompt differentiation from common cellulitis is vital for timely intervention.
  • This condition may lead to more frequent severe visual loss than previously understood.