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Critical phase among patients with dengue fever during the 2010 outbreak in Nepal
Sher Bahadur Pun1, Yogendra Shah
1Clinical Research Unit, Sukraraj Tropical and Infectious Disease Hospital, Kathmandu, Nepal. drsherbdr@yahoo.com
Background:
Dengue virus infection has become an increasingly serious threat to public health in Nepal. Detection and/or serotyping of dengue virus has been reported in the past; however, little is known about the critical phase among dengue patients in Nepal.
Methods:
Rapid immunochromatographic tests and reverse transcription PCR (RT-PCR) were performed in order to diagnosis dengue fever. Ultrasonographic and chest radiography were used to identify the plasma leakage phase.
Results:
Of the total 264 patients with dengue, 8.7% (23/264) were admitted during the critical phase; 82.6% (19/23) of the patients were between 20 and 44 years of age.
Conclusion:
Physicians need to be vigilant and attentive to young adult patients with dengue fever.
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