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Related Concept Videos

Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...

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Related Experiment Video

Updated: May 9, 2026

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
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Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

Gene therapy in periodontics.

Anirban Chatterjee1, Nidhi Singh, Mini Saluja

  • 1Department of Periodontics, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India.

Journal of Indian Society of Periodontology
|July 23, 2013
PubMed
Summary

Gene therapy uses DNA to repair faulty genes, offering a promising medical treatment. This approach is being explored in periodontics for tissue engineering to reconstruct damaged gum and bone tissues.

Keywords:
Designer drug therapygene deliverygene therapyscaffoldsignaling molecule

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Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
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Three-dimensional Inflammatory Human Tissue Equivalents of Gingiva
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Three-dimensional Inflammatory Human Tissue Equivalents of Gingiva

Published on: April 3, 2018

Area of Science:

  • Genetics and Molecular Biology
  • Regenerative Medicine
  • Periodontics

Background:

  • Genes, composed of DNA, contain inherited instructions, and alterations can lead to diseases.
  • Gene therapy involves introducing functional gene copies to repair or replace faulty genes.
  • Periodontal disease affects the tissues supporting the teeth, including bone and ligaments.

Purpose of the Study:

  • To explore the application of gene therapy in periodontics.
  • To investigate gene therapy as a mode of tissue engineering for periodontal reconstruction.

Main Methods:

  • Gene therapy involves transferring therapeutic genes into specific cells.
  • Tissue engineering combines scaffolds, signaling molecules, cells, and blood supply for tissue reconstruction.
  • The study discusses the potential of these combined approaches in periodontics.

Main Results:

  • Gene therapy offers a promising therapeutic strategy for various conditions.
  • Tissue engineering facilitates the reconstruction of damaged periodontium.
  • The integration of gene therapy and tissue engineering shows potential for periodontal regeneration.

Conclusions:

  • Gene therapy presents a novel medical treatment paradigm.
  • The combination of gene therapy and tissue engineering holds significant promise for periodontal regeneration.
  • This approach can aid in reconstructing damaged cementum, gingival, periodontal ligament, and bone.