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Hepatitis D virus in Victoria 2000-2009
B Shadur1, J MacLachlan, B Cowie
1WHO Regional Reference Laboratory for Hepatitis B, Victorian Infectious Disease Reference Laboratory, Melbourne, Victoria, Australia.
Internal Medicine Journal
|July 23, 2013
Summary
Hepatitis D virus (HDV) testing increased in Victoria, Australia, but follow-up care for positive cases remains insufficient. Routine screening for chronic hepatitis B patients is recommended, especially for those born overseas.
Area of Science:
- Hepatology
- Virology
- Public Health
Background:
- Hepatitis D virus (HDV) coinfection complicates management of chronic hepatitis B.
- Epidemiology and clinical practices for HDV in Australia are not well understood.
- There is a lack of data on HDV disease burden and follow-up care in Australia.
Purpose of the Study:
- To determine the number of reported HDV cases in Victoria, Australia (2000-2009).
- To explore screening practices for patients at risk of HDV infection during the same period.
Main Methods:
- Utilized notifiable disease surveillance and public health laboratory records for HDV diagnoses in Victoria (2000-2009).
- Analyzed notification data for demographics and risk factors.
- Examined laboratory records for screening and follow-up testing practices.
Main Results:
- Eighty-seven HDV notifications were recorded between 2000-2009.
- 2314 Victorian residents were tested, with 110 (4.75%) positive; testing and positive results increased from 2005-2009.
- Only 40% of positive HDV antibody cases received follow-up testing for replicative infection.
Conclusions:
- HDV testing has increased, but appropriate follow-up for infected patients is lacking.
- Being born overseas is an emerging risk factor for HDV.
- Routine HDV testing is needed for individuals with chronic hepatitis B.
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