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Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

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Lumbar artificial intervertebral disc replacement: a systematic review.

Prema Thavaneswaran¹, Meegan Vandepeer

¹Australian Safety and Efficacy Register of New Interventional Procedures - Surgical (ASERNIP-S), Royal Australasian College of Surgeons, Adelaide, South Australia, Australia.

ANZ Journal of Surgery

|July 23, 2013

Summary

This summary is machine-generated.

Lumbar artificial intervertebral disc replacement (AIDR) shows comparable short-term safety and effectiveness to lumbar fusion for treating low back pain. AIDR outcomes, including pain reduction and patient satisfaction, were often better than fusion.

Keywords:

intervertebral disc degeneration low back pain lumbar vertebrae prosthesis implantation review

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Area of Science:

Spine surgery
Biomedical engineering
Orthopedics

Background:

Low back pain is a major health issue in Australia.
Lumbar artificial intervertebral disc replacement (AIDR) is an alternative to lumbar fusion for degenerative disc disease.
AIDR addresses axial low back pain caused by degenerative disc disease.

Purpose of the Study:

To evaluate the safety and effectiveness of lumbar AIDR.
To assess AIDR for axial or radicular pain from disc degeneration/prolapse unresponsive to non-operative care.

Main Methods:

Systematic search of electronic databases (Jan 2005-Apr 2012).
Included randomized controlled trials and non-randomized comparative studies.
Two independent reviewers applied a predetermined protocol for study inclusion.

Main Results:

Six RCTs (nine studies) and one non-randomized study compared lumbar AIDR with lumbar fusion.
Adverse event rates were similar between AIDR and fusion groups; serious events were rare.
Lumbar AIDR demonstrated significantly better or equivalent effectiveness outcomes compared to lumbar fusion.

Conclusions:

Short to medium-term safety of lumbar AIDR is comparable to lumbar fusion.
Short to medium-term effectiveness of lumbar AIDR is comparable to lumbar fusion.