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Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies
Published on: April 11, 2012
Multidrug-resistant Pseudomonas aeruginosa: a case of pyelonephritis and herbal therapy
YanQing Tong1, Min Sun, ChuFeng Wang
1Department of Nephrology, The First Affiliated Hospital to Changchun University of Chinese Medicine , Changchun City, Jilin Province, China .
Abstract:
Multidrug-resistant Pseudomonas aeruginosa, which was only susceptible to colistin, was isolated from the urine of a patient with pyelonephritis. The isolates were confirmed as class A Extended-spectrum-β-lactamase-producing isolates. A blaBEL allele was detected by multiplex polymerase chain reaction. The organisms were identified as ST235, serotype O11. Chinese herbal decoction was orally administered. The patient returned 8 days later with relief of symptoms. No P. aeruginosa was isolated from two urine samples taken after 1 week and 2 weeks from the end of herbal therapy. The case supports the notion that these Chinese herbs are useful in treating pyelonephritis caused by multidrug-resistant P. aeruginosa. Chinese herbal medicine has allowed another choice of treatment.
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