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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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Related Experiment Video

Updated: May 9, 2026

Initial Evaluation of Antibody-conjugates Modified with Viral-derived Peptides for Increasing Cellular Accumulation and Improving Tumor Targeting
11:58

Initial Evaluation of Antibody-conjugates Modified with Viral-derived Peptides for Increasing Cellular Accumulation and Improving Tumor Targeting

Published on: March 8, 2018

Advances in anticancer radiopharmaceuticals.

M R Jackson1, N Falzone, K A Vallis

  • 1CR-UK/MRC Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK.

Clinical Oncology (Royal College of Radiologists (Great Britain))
|July 23, 2013
PubMed
Summary

Recent advancements in anticancer radiopharmaceuticals enable targeted delivery of radioactive isotopes to cancer cells. Innovations in molecular targeting, antibody engineering, and nanotechnology are expanding therapeutic options for cancer treatment.

Keywords:
radioimmunotherapytargeted radiotherapyvectorsα Particlesβ electrons

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Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
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Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

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Initial Evaluation of Antibody-conjugates Modified with Viral-derived Peptides for Increasing Cellular Accumulation and Improving Tumor Targeting
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Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
09:44

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

Area of Science:

  • Oncology
  • Nuclear Medicine
  • Radiopharmaceutical Chemistry

Background:

  • Molecularly targeted radiotherapy selectively delivers radionuclides to cancer cells.
  • New molecular targets are being identified through systems biology.
  • Advances in drug delivery technologies are crucial for effective targeted radiotherapy.

Purpose of the Study:

  • To review recent progress in the development of anticancer radiopharmaceuticals.
  • To highlight innovations in radionuclide delivery systems.
  • To discuss the expanding scope of targeted radiotherapy.

Main Methods:

  • Review of recent literature on radiopharmaceutical development.
  • Analysis of innovations in antibody engineering, recombinant DNA technology, and nanotechnology.
  • Examination of emerging radioisotopes for targeted therapy.

Main Results:

  • Development of novel targeting vectors for selective radionuclide delivery.
  • Improvements in antibody engineering and conjugation chemistry for enhanced targeting.
  • Increased availability and application of alpha particle emitters and other radioisotopes.

Conclusions:

  • Targeted radiotherapy holds significant promise for cancer treatment.
  • Continued innovation in molecular targeting and delivery systems will expand therapeutic applications.
  • Emerging radioisotopes offer new avenues for effective cancer therapy.