Related Experiment Video
Updated: May 9, 2026
08:56
Visual Detection of Multiple Nucleic Acids in a Capillary Array
Published on: November 15, 2017
Biomolecular analysis with microring resonators: applications in multiplexed diagnostics and interaction screening
1Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Matthews Avenue, Urbana, IL 61801, United States.
Current Opinion in Chemical Biology
|July 23, 2013
Summary
Microring optical resonators offer sensitive and versatile biosensing for detecting various biological targets. This technology, originally from telecommunications, is rapidly advancing for bioanalytical applications.
Area of Science:
- Biotechnology
- Optical Engineering
- Analytical Chemistry
Background:
- Microring resonators, initially for telecommunications, are emerging as powerful biosensors.
- Their sensitivity stems from light-matter interactions and sensitivity to refractive index changes.
Purpose of the Study:
- To highlight recent advancements in microring resonator biosensing.
- To explore future potential in bioanalytical applications.
Main Methods:
- Utilizing light propagation and evanescent fields within microring structures.
- Monitoring shifts in resonant wavelength due to environmental refractive index changes.
Main Results:
- Demonstrated detection of proteins, nucleic acids, viruses, and small molecules.
- Showcased scalability, sensitivity, and versatility for diverse targets.
Conclusions:
- Microring resonators show significant promise for future bioanalytical sensing.
- Continued development is expected to expand their applications in life sciences.
More Related Videos
Related Concept Videos
01:24Automated Microbial Diagnostics
Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
01:17Microbial Biosensors
Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...