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Related Experiment Video

Updated: May 9, 2026

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications
07:40

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications

Published on: June 29, 2020

Current and future tools for global canine rabies elimination.

Richard Franka1, Todd G Smith, Jessie L Dyer

  • 1Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mail Stop G33, Atlanta, GA 30333, USA.

Antiviral Research
|July 23, 2013
PubMed
Summary

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Rabies is preventable through vaccination and prompt post-exposure prophylaxis. Eliminating canine rabies via herd immunity and community education is the most cost-effective long-term strategy.

Area of Science:

  • Veterinary Public Health
  • Infectious Disease Control
  • One Health Initiative

Background:

  • Rabies is nearly always fatal but preventable with vaccines and immune globulin.
  • Limited access to and knowledge of rabies prevention tools hinder efforts in high-burden countries.
  • Inappropriate use of vaccines and immune globulin leads to shortages and preventable deaths.

Purpose of the Study:

  • To highlight the cost-effectiveness of canine rabies elimination for long-term human rabies prevention.
  • To advocate for a "One Health" strategy focusing on sustainable canine vaccination and community engagement.
  • To identify key components for successful canine rabies elimination programs.

Main Methods:

  • Review of successful canine rabies elimination strategies globally.
Keywords:
EducationEliminationPreventionProphylaxisRabiesVaccine

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Last Updated: May 9, 2026

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications
07:40

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications

Published on: June 29, 2020

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
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Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology

Published on: August 18, 2023

  • Analysis of the "One Health" approach integrating animal and human health.
  • Identification of essential elements for community-based vaccination programs.
  • Main Results:

    • Canine rabies elimination is more cost-effective than solely focusing on human prophylaxis.
    • Community-based, locally guided dog vaccination programs achieve sustainable herd immunity.
    • Successful programs require government support, international collaboration, and long-term commitment.

    Conclusions:

    • Focusing on eliminating canine rabies is crucial for preventing human deaths.
    • A "One Health" strategy with community education and humane population management is effective.
    • Future advancements include new vaccine technologies, diagnostics, and canine immunocontraceptives.