Health-related quality of life in the elderly three years after percutaneous coronary intervention

Anna Panasewicz1, Susanne S Pedersen, Stefanie J G Veenhuis

  • 1Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.

Insights

Elderly patients undergoing percutaneous coronary intervention (PCI) experience declining health-related quality of life (HRQOL) compared to younger individuals. Predictors of poor HRQOL also differ between these age groups.

Area of Science:

  • Cardiology
  • Geriatrics
  • Health Services Research

Background:

  • Long-term health-related quality of life (HRQOL) after percutaneous coronary intervention (PCI) in elderly populations remains understudied.
  • Understanding age-related differences in HRQOL post-PCI is crucial for patient-centered care.

Purpose of the Study:

  • To compare HRQOL between elderly (≥70 years) and younger (<70 years) patients at 6, 12, and 36 months post-PCI.
  • To identify differing predictors of impaired HRQOL at 36 months post-PCI in elderly versus younger patients.

Main Methods:

  • A prospective cohort study of 651 PCI patients, with 26.3% aged 70 years or older.
  • Utilized the SF-36 questionnaire to assess HRQOL at 6, 12, and 36 months post-PCI.

Main Results:

  • Older patients reported poorer physical HRQOL and worse mental HRQOL (vitality, role emotional) at all time points (p<0.05).
  • By 36 months, elderly patients showed worsening HRQOL in five of eight domains (p<0.05), while younger patients had stable HRQOL except for role physical functioning.
  • Predictors of impaired HRQOL differed: elderly (diabetes, prior PCI), younger (smoking, prior bypass surgery, ACE inhibitors), with anxiety and depression common to both.

Conclusions:

  • Elderly PCI patients experience a significantly poorer and deteriorating HRQOL over three years compared to younger patients.
  • Unlike younger patients, the three-year HRQOL in elderly patients was not influenced by adverse outcomes.
Abstract

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