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Published on: August 24, 2019
Health-related quality of life in the elderly three years after percutaneous coronary intervention
Anna Panasewicz1, Susanne S Pedersen, Stefanie J G Veenhuis
1Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
Insights
Elderly patients undergoing percutaneous coronary intervention (PCI) experience declining health-related quality of life (HRQOL) compared to younger individuals. Predictors of poor HRQOL also differ between these age groups.
Area of Science:
- Cardiology
- Geriatrics
- Health Services Research
Background:
- Long-term health-related quality of life (HRQOL) after percutaneous coronary intervention (PCI) in elderly populations remains understudied.
- Understanding age-related differences in HRQOL post-PCI is crucial for patient-centered care.
Purpose of the Study:
- To compare HRQOL between elderly (≥70 years) and younger (<70 years) patients at 6, 12, and 36 months post-PCI.
- To identify differing predictors of impaired HRQOL at 36 months post-PCI in elderly versus younger patients.
Main Methods:
- A prospective cohort study of 651 PCI patients, with 26.3% aged 70 years or older.
- Utilized the SF-36 questionnaire to assess HRQOL at 6, 12, and 36 months post-PCI.
Main Results:
- Older patients reported poorer physical HRQOL and worse mental HRQOL (vitality, role emotional) at all time points (p<0.05).
- By 36 months, elderly patients showed worsening HRQOL in five of eight domains (p<0.05), while younger patients had stable HRQOL except for role physical functioning.
- Predictors of impaired HRQOL differed: elderly (diabetes, prior PCI), younger (smoking, prior bypass surgery, ACE inhibitors), with anxiety and depression common to both.
Conclusions:
- Elderly PCI patients experience a significantly poorer and deteriorating HRQOL over three years compared to younger patients.
- Unlike younger patients, the three-year HRQOL in elderly patients was not influenced by adverse outcomes.
Aims:
Long-term health-related quality of life (HRQOL) in the elderly after percutaneous coronary intervention (PCI) is unknown. We 1) compared HRQOL of elderly (≥70 years) with younger patients (<70 years) at 6, 12, 36 months post-PCI, and 2) examined whether predictors of impaired HRQOL 36 months post-PCI differed between older and younger patients.
Methods And Results:
A prospective cohort of 651 PCI patients (26.3% ≥70 years) completed the SF-36 at 6, 12 and 36 months post-PCI. Older patients experienced a poorer physical HRQOL at all time points and worse mental HRQOL with respect to vitality and role emotional functioning (all p-values<0.05). By 36 months, the HRQOL for the older patients worsened in five of the eight subdomains (all p-values<0.05). Younger patients did not experience enduring changes in HRQOL, with the exception of role physical functioning. Predictors of impaired HRQOL were generally different for the elderly (diabetes, previous PCI) compared to younger cohorts (smoking, previous bypass surgery, ACE inhibitors), although poor six-month HRQOL, anxiety and depression were common predictors for both groups.
Conclusions:
Elderly PCI patients experience a deteriorating and poorer HRQOL than younger patients across three years. Contrary to younger patients, three-year HRQOL of elderly patients is irrespective of adverse events during outcomes.
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