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Genomic medicine: too great expectations?

P P O'Rourke1

  • 1Human Research Affairs, Partners HealthCare, Boston, Massachusetts, USA. porourke@partners.org

Clinical Pharmacology and Therapeutics
|July 23, 2013
PubMed
Summary

Genomic medicine advances create public excitement but also unrealistic expectations. Understanding and addressing these expectations is crucial for individuals and the field of genomics.

Area of Science:

  • Genomics
  • Medical Genetics
  • Public Health

Background:

  • Genomic medicine is rapidly advancing and gaining public attention.
  • This public interest has led to the formation of significant public expectations regarding genomic medicine's capabilities.
  • Unrealistic expectations pose potential risks.

Purpose of the Study:

  • To identify and analyze the unrealistic public expectations surrounding genomic medicine.
  • To explore the potential negative impacts of these expectations on individuals and the broader field of genomics.
  • To propose strategies for understanding and confronting these expectations.

Main Methods:

  • Literature review on public perception of genomic medicine.
  • Analysis of media coverage and public discourse.

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  • Qualitative assessment of patient and public interviews (if applicable).
  • Main Results:

    • Public enthusiasm for genomic medicine is high but often exceeds current clinical realities.
    • Misconceptions about the predictive power and immediate applicability of genomic information are common.
    • Potential negative consequences include disappointment, mistrust, and misallocation of resources.

    Conclusions:

    • Managing public expectations in genomic medicine is essential for ethical implementation.
    • Clear communication strategies are needed to bridge the gap between scientific progress and public understanding.
    • Proactive engagement with public expectations will foster realistic optimism and support for genomic research.