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Related Concept Videos

Introduction Cardiac Emergencies01:30

Introduction Cardiac Emergencies

Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Such genes that act...
Peptic Ulcer01:27

Peptic Ulcer

Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the mucus...
Nursing Ethical Principles II01:27

Nursing Ethical Principles II

Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
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Updated: May 9, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

Identifying oncological emergencies.

Achuta K Guddati1, Nilay Kumar, Ankur Segon

  • 1Department of Internal Medicine, Harvard Medical School, Massachusetts General Hospital, Harvard University, 50 Fruit Street, Boston, MA, USA. aguddati@partners.org

Medical Oncology (Northwood, London, England)
|July 23, 2013
PubMed
Summary
This summary is machine-generated.

Prompt recognition and management of life-threatening oncological emergencies are crucial. These conditions, presenting diversely, require advanced diagnostics for timely intervention and improved patient outcomes.

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Area of Science:

  • Oncology
  • Emergency Medicine

Background:

  • Life-threatening oncological emergencies require prompt diagnosis and treatment.
  • These emergencies present with diverse symptoms, including mechanical obstruction and metabolic disturbances.
  • Hematologic and infectious complications can mask or exacerbate oncological emergencies.

Purpose of the Study:

  • To emphasize the importance of including oncological emergencies in differential diagnoses.
  • To highlight the varied presentations and diagnostic challenges of oncological emergencies.
  • To underscore the impact of early diagnosis and treatment on patient outcomes.

Main Methods:

  • Review of clinical presentations of oncological emergencies.
  • Emphasis on the role of advanced testing and imaging in diagnosis.
  • Consideration of complicating hematologic and infectious conditions.

Main Results:

  • Oncological emergencies manifest through various mechanisms, such as tumor obstruction or abnormal secretions.
  • Diagnosis often necessitates advanced investigations.
  • Coexisting hematologic or infectious issues can complicate patient presentation.

Conclusions:

  • Oncological emergencies are critical conditions demanding immediate attention.
  • A broad differential diagnosis is essential for prompt identification.
  • Timely intervention significantly improves clinical outcomes for patients with oncological emergencies.