Risk factors for choroidal detachment after trabeculectomy with mitomycin C

Area of Science:

• Ophthalmology
• Surgical Innovation
• Glaucoma Research

Background:

• Trabeculectomy with mitomycin C (MMC) is a common glaucoma surgery.
• Choroidal detachment is a potential complication following this procedure.
• Identifying risk factors is crucial for patient management and surgical outcomes.

Purpose of the Study:

• To investigate the risk factors associated with choroidal detachment after trabeculectomy with MMC.
• To analyze patient demographics and surgical parameters influencing this complication.

Main Methods:

• Retrospective analysis of 420 glaucoma patients undergoing trabeculectomy with MMC.
• Logistic multivariable analysis to identify significant risk factors.
• Assessment included age, gender, glaucoma type, preoperative and postoperative intraocular pressure (IOP), and laser suture lysis.

Main Results:

• Choroidal detachment occurred in 18.8% of patients, typically within 6 days post-surgery.
• Older age (OR=1.028/year) and lower postoperative IOP (OR=0.887/mmHg) were significant risk factors.
• These factors remained significant in the subgroup of open-angle glaucoma patients.

Conclusions:

• Older age and lower postoperative IOP are identified as independent risk factors for choroidal detachment after trabeculectomy with MMC.
• These findings are applicable to the general glaucoma population and specifically to open-angle glaucoma cases.
• Understanding these risk factors can aid in preventing and managing postoperative choroidal detachment.