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Updated: May 9, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
Abstract:
The increasing number of invasive procedures done with contrast agents makes the prevention of their induced nephropathy more urgent. At present, different methods are being developed to prevent contrast-induced nephropathy (CIN) with antioxidants, intrarenal vasodilators, hydration therapy, by accurately determining the amount of excreted fluid obtained from a urinary catheter and less toxic iodine-containing contrast agents are being put into practice. Unfortunately, the current guidelines for the prevention of CIN are inadequately followed in both Russia and foreign countries. This review covers the main components of the pathogenesis and risk factors of this pathology and its possible preventive measures.
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