Stage II endometrial carcinoma: prognostic factors and the results of treatment

Results of treatment and potential prognostic factors in 54 patients with clinical stage II endometrial carcinoma were analyzed. During the period analyzed, three different treatment techniques were used. The highest cure rate (70.6%) was observed in patients treated with simple hysterectomy and bilateral salpingo-oophorectomy followed by external pelvic irradiation and vaginal irradiation. Radiation therapy alone cured 50%. High tumor grade, deep myometrial invasion (greater than 50%), and invasion of the cervical stroma reduced the cure rates, but the only factor significantly reducing cure rate was patient age. Patients 59 years of age or older fared significantly more poorly than younger patients. Significant complications was observed in 9.3% of patients. Prospective studies of standardized treatment techniques in patients with stage II endometrial carcinoma are necessary to achieve better results and acquire more information.