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Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
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Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
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Related Experiment Video

Updated: May 9, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
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Failure to pass meconium.

Luis Lizardo Sanchéz1, Humberto Lugo-Vicente

  • 1UPR School of Medicine, San Juan, PR 00922.

Boletin De La Asociacion Medica De Puerto Rico
|July 24, 2013
PubMed
Summary
This summary is machine-generated.

Failure to pass meconium within 24 hours suggests congenital low gastrointestinal obstruction. This review outlines a systematic approach for accurate diagnosis and management of common causes in neonates.

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Area of Science:

  • Neonatal Medicine
  • Pediatric Surgery
  • Gastroenterology

Background:

  • Delayed meconium passage in newborns is a critical indicator of potential gastrointestinal abnormalities.
  • Congenital low alimentary tract obstruction requires timely diagnosis and intervention to prevent serious complications.

Purpose of the Study:

  • To provide a systematic diagnostic and management framework for clinicians encountering neonatal delayed meconium passage.
  • To review common etiologies, diagnostic modalities, and therapeutic strategies for congenital low alimentary tract obstruction.

Main Methods:

  • Systematic review of literature on neonatal gastrointestinal obstruction.
  • Analysis of diagnostic approaches including prenatal and postnatal methods.
  • Evaluation of imaging techniques and differential diagnoses.

Main Results:

  • Failure to pass meconium within the first 24 hours of life is a significant sign of obstruction.
  • A structured approach aids in differentiating various causes of delayed meconium passage.
  • Common causes include meconium ileus, intestinal atresia, and Hirschsprung disease.

Conclusions:

  • Early recognition and systematic evaluation are crucial for managing neonatal gastrointestinal obstruction.
  • Comprehensive diagnostic workup, including imaging, is essential for identifying the underlying cause.
  • Prompt and appropriate management improves outcomes for neonates with congenital low alimentary tract obstruction.