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Updated: May 9, 2026

Sample Preparation for Probe Electrospray Ionization Mass Spectrometry
Published on: February 19, 2020
Development of sheath-flow probe electrospray ionization mass spectrometry and its application to real time pesticide
Mridul Kanti Mandal1, Tomoyuki Ozawa, Subhrakanti Saha
1Clean Energy Research Center, University of Yamanashi, Kofu, Yamanashi, Japan. mandal@yamanashi.ac.jp
Abstract:
For the real time and direct analysis of chemical constituents from living beings and dry sample, sheath-flow probe electrospray ionization mass spectrometry (SF-PESI-MS) has been newly developed. The components from dry or semidry biological tissues can be extracted using the solvent and picked up by the needle for electrospray. This technique was applied to real-time pesticide analysis of living plants. The results have been validated with that of a well-known system, liquid extraction surface analysis mass spectrometry (LESA-MS). It is demonstrated that SF-PESI-MS can produce reasonable ionization efficiency, which is confirmed by LESA-MS.
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