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Genetic changes in nonepithelial ovarian cancer

Els Van Nieuwenhuysen1, Sandrina Lambrechts, Diether Lambrechts

  • 1Division of Gynecological Oncology, Department of Obstetrics and Gynecology, Leuven Cancer Institute, University Hospitals Leuven, Belgium. els.vannieuwenhuysen@uzleuven.be

Expert Review of Anticancer Therapy
|July 24, 2013
PubMed
Summary

Genetic alterations in rare ovarian cancers like sex cord-stromal tumors (SCSTs) and germ cell tumors (GCTs) are being uncovered. Key mutations in FOXL2 and DICER1, and susceptibility loci in GCTs, offer insights into their development.

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