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Updated: May 9, 2026
Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex
Published on: August 17, 2018
Transcranial magnetic stimulation for refractory focal status epilepticus in the intensive care unit
Anli Liu1, Trudy Pang, Susan Herman
1New York University Comprehensive Epilepsy Center, 223 East 34th Street, New York, NY 10016, USA; New York University Langone Medical Center and School of Medicine, 550 First Avenue, New York, NY 10016 USA.
Purpose:
To examine the efficacy and safety profile of antiepileptic repetitive transcranial magnetic stimulation (rTMS) for refractory status epilepticus (RSE) in the intensive care unit (ICU) setting. In addition, hypothetical concerns about electrical interference of rTMS with ICU equipment have been previously raised.
Methods:
We describe two cases of RSE treated with rTMS in the ICU.
Results:
In one case, rTMS contributed to decreased seizure frequency; in the second case, rTMS transiently decreased seizure frequency. In both cases, rTMS was safe and did not interfere with the functioning of the ICU equipment.
Conclusion:
rTMS is a potential therapy for RSE when conventional therapies have failed. Future studies should investigate the efficacy of various rTMS stimulation parameters, safety issues, and bioengineering considerations in the ICU setting.
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