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Related Experiment Video

Updated: May 9, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Central giant cell granuloma: a case report.

Ravi Prakash Sasankoti Mohan1, Sankalp Verma, Neha Agarwal

  • 1Department of Oral Medicine & Radiology, Kothiwal Dental College & Research Center, Moradabad, Uttar Pradesh, India. sasan_ravi@rediffmail.com

BMJ Case Reports
|July 24, 2013
PubMed
Summary

Central giant cell granuloma (CGCG) is a rare, benign jaw lesion. This case highlights a pediatric patient with CGCG in the mandible, emphasizing its asymptomatic presentation.

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Pediatric Dentistry
  • Pathology

Background:

  • Central giant cell granuloma (CGCG) is an uncommon benign bone lesion.
  • Historically considered a reactive lesion, its exact etiology is debated.
  • CGCG exhibits variable degrees of aggressiveness.

Observation:

  • CGCG often presents asymptomatically, detected incidentally on radiographs.
  • Lesions can manifest as painless, visible expansion of the affected jaw.
  • This report details a case in a 4-year-old boy with mandibular CGCG.

Findings:

  • The case involves a pediatric patient with a central giant cell granuloma.
  • The lesion was located in the right mandibular region.
  • The presentation was consistent with typical CGCG characteristics.

Related Experiment Videos

Last Updated: May 9, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Implications:

  • Early detection of CGCG is crucial for effective management.
  • Understanding CGCG in pediatric populations is important for long-term outcomes.
  • This case contributes to the literature on rare pediatric jaw lesions.