Lifting the veil on amyloid drug design
Kathryn E Tiller1, Peter M Tessier
1is in the Center for Biotechnology & Interdisciplinary Studies, Department of Chemical and Biological Engineering , Rensselaer Polytechnic Institute , New York , United States tillek@rpi.edu.
Elife
|July 24, 2013
Abstract:
High resolution structures and computational methods have been used to identify compounds that prevent amyloid fibrils associated with Alzheimer's disease from dissociating into toxic species.
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