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Updated: May 9, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
[Coronary calcinosis. State-of-the-art]
Insights
Coronary artery calcification, a marker of atherosclerosis, is linked to cardiovascular disease risk. A high calcium score indicates higher risk, but effective treatments for coronary calcification require further study.
Area of Science:
- Cardiovascular medicine
- Radiology
- Medical imaging
Background:
- Atherosclerosis and coronary heart disease are leading causes of death and disability globally.
- Coronary artery calcification is a significant indicator of atherosclerotic plaque burden.
- The extent of calcification correlates with the severity of atherosclerotic lesions.
Purpose of the Study:
- To highlight the significance of coronary artery calcification in cardiovascular disease.
- To emphasize the role of calcium scoring in risk assessment.
- To underscore the need for further research into effective treatments for coronary calcification.
Main Methods:
- Utilizing multispiral and electron-beam computed tomography (CT) for quantitative assessment.
- Characterizing coronary calcinosis through the determination of calcium scores.
- Reviewing clinical studies correlating calcium scores with atherosclerotic lesions and cardiovascular risk.
Main Results:
- Coronary calcinosis is quantitatively measured by calcium scores derived from CT scans.
- A high calcium score is indicative of an elevated risk for cardiovascular complications.
- The area of calcification constitutes approximately one-fifth of the atherosclerotic plaque area.
Conclusions:
- Coronary artery calcification is a critical marker in assessing cardiovascular risk.
- Accurate quantification via calcium scoring aids in risk stratification.
- Further investigation is necessary to establish optimal therapeutic strategies for managing coronary calcification.
Abstract:
Atherosclerosis and coronary heart disease are the main causes of disablement and mortality in most developed countries. Clinical studies showed the relationship between coronary calcinosis and atherosclerotic lesions, the calcinosis area accounting for roughly 1/5 of the atherosclerotic plaque area. Calcinosis is quantitatively characterized by the calcium score determined by multispiral and electron-beam computed tomography. High calcium score suggests an increased risk of cardiovascular complications. Their treatment awaits further assessment since a number of studies revealed differential effect of various medicines on coronary calcification.
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