Related Experiment Video
Updated: May 9, 2026

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
Value of electro-vectorcardiogram in hypertrophic cardiomyopathy
Andrés Ricardo Pérez-Riera1, Augusto Armando de Lucca, Raimundo Barbosa-Barros
1Cardiology Discipline, ABC Faculty of Medicine, ABC Foundation, Santo André, São Paulo, Brazil. riera@uol.com.br
Insights
The electrocardiogram (ECG) is highly effective for diagnosing hypertrophic cardiomyopathy (HCM), detecting anomalies in over 90% of cases. Despite its sensitivity, its role in pre-participation screening for athletes remains debated.
Area of Science:
- Cardiology
- Medical Diagnostics
Background:
- Hypertrophic cardiomyopathy (HCM) is a significant cause of sudden cardiac death in young athletes.
- Electrocardiogram (ECG) anomalies are prevalent in HCM, often appearing earlier and more sensitively than echocardiographic findings.
Purpose of the Study:
- To highlight the diagnostic utility of ECG in identifying hypertrophic cardiomyopathy.
- To discuss the prognostic implications of specific ECG findings in HCM patients.
Main Methods:
- Analysis of electrocardiographic patterns in various forms of hypertrophic cardiomyopathy.
- Correlation of ECG findings with clinical presentation and outcomes.
Main Results:
- ECG alterations are present in over 90% of HCM cases, preceding echocardiographic changes.
- Specific ECG hallmarks, like giant negative T waves in apical HCM, are identified.
- Ventricular tachycardias and conduction blocks on ECG are associated with poor prognosis or post-treatment status.
Conclusions:
- ECG is a crucial initial diagnostic tool for hypertrophic cardiomyopathy.
- Certain ECG findings serve as important prognostic markers in HCM.
- The role of ECG in athlete screening requires further consensus despite its diagnostic value.
Abstract:
The electrocardiogram is an important tool for the initial diagnostic suspicion of hypertrophic cardiomyopathy in any of its forms, both in symptomatic and in asymptomatic patients because it is altered in more than 90 percent of the cases. Electrocardiographic anomalies are more common in patients carriers of manifest hypertrophic cardiomyopathy and the electrocardiogram alterations are earlier and more sensitive than the increase in left ventricular wall thickness detected by the echocardiogram. Nevertheless, despite being the leading cause of sudden death among young competitive athletes there is no consensus over the need to include the method in the pre-participation screening. In apical hypertrophic cardiomyopathy the electrocardiographic hallmarks are the giant negative T waves in anterior precordial leads. In the vectorcardiogram, the QRS loop is located predominantly in the left anterior quadrant and T loop in the opposite right posterior quadrant, which justifies the deeply negative T waves recorded. The method allows estimating the left ventricular mass because it relates to the maximal spatial vector voltage of the left ventricle in the QRS loop. The recording on electrocardiogram or Holter monitoring of nonsustained monomorphic ventricular tachycardia in patients with syncope, recurrent syncope in young patient, hypotension induced by strain, bradyarrhythmia, or concealed conduction are markers of poor prognosis. The presence of rare sustained ventricular tachycardia is observed in mid-septal obstructive HCM with apical aneurysm. The presence of complete right bundle branch block pattern is frequent after the percutaneous treatment and complete left bundle branch block is the rule after myectomy.
Related Concept Videos
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...
Electrocardiogram Fundamentals
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin to...
Cardiomyopathy II: Dilated Cardiomyopathy
Dysrhythmias V: Evaluating Dysrhythmias
Cardiomyopathy V: Interprofessional Care
