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[Combined treatment: regimens, indications and safety profile]
Ovidio Muñiz Grijalvo1, Jose Villar Ortiz
1UCERV, Servicio de Medicina Interna, Hospital Virgen del Rocío, Sevilla, España.
Abstract:
Statins are the current basis of lipid-lowering therapy, despite which may have limitations on efficacy and safety. In high risk patients who do not achieve current lipid goals, in those intolerant to statins or those with atherogenic dyslipidemia, it is possible combine two or more lipid lowering drugs, including statins, ezetimibe, bile acid sequestrants, fibrates, niacin and prescription omega-3 fatty acids. However, for most of these combination therapies pivotal data on clinical outcomes are still lacking.
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