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Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
Published on: November 9, 2018
A child with altered sensorium, hyperglycemia, and elevated troponins
Rajan Arora1, Saurabh Chiwane1, Earl Hartwig1
1Carman and Ann Adam Department of Pediatrics, Children's Hospital of Michigan, Detroit, Michigan.
Insights
Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) can present with overlapping symptoms in children, complicating diagnosis. Prompt recognition of these diabetic emergencies is crucial for effective treatment and improved patient outcomes.
Area of Science:
- Pediatric Endocrinology
- Emergency Medicine
- Metabolic Disorders
Background:
- Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are severe diabetes mellitus complications.
- DKA and HHS are distinct entities requiring tailored management strategies.
- Distinguishing between DKA and HHS can be challenging, particularly in pediatric patients.
Observation:
- A 12-year-old presented with a mixed picture of DKA and HHS coma.
- The patient experienced myocardial strain and acute renal insufficiency.
- Metabolic derangements were identified as the cause of the patient's complications.
Findings:
- The case highlights the diagnostic difficulty in differentiating DKA and HHS in children.
- Overlapping clinical features can obscure the precise diagnosis.
- Myocardial strain and acute renal insufficiency were noted complications.
Implications:
- Emergency physicians must be aware of diverse hyperglycemic emergency presentations in children.
- Accurate diagnosis is essential for initiating appropriate and timely treatment.
- Recognizing varied presentations improves management and patient outcomes in pediatric diabetes emergencies.
Background:
Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are potentially life-threatening complications of diabetes mellitus. Although DKA and HHS share similar features, they are distinct clinical entities requiring different treatment measures.
Objective:
This case illustrates that the clinical distinction between these two entities can be difficult at times, especially in children who can present with an overlapping picture.
Case Report:
We report an interesting case of a 12-year-old whose initial presentation of diabetes was a mixed picture of hyperosmolar DKA and HHS coma complicated by myocardial strain and acute renal insufficiency. The myocardial strain resolved completely with resolution of the metabolic abnormalities.
Conclusions:
Emergency physicians should be cognizant of varied presentations of hyperglycemic emergencies in children to initiate appropriate management for better outcomes.
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