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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Placental HTR2A methylation is associated with infant neurobehavioral outcomes

Alison G Paquette1, Corina Lesseur, David A Armstrong

  • 1Department of Pharmacology and Toxicology; Geisel School of Medicine at Dartmouth; Dartmouth, NH USA.

Epigenetics
|July 25, 2013
PubMed

Keywords:
DNA methylationHTR2Abehaviordevelopmental origins of diseaseepigeneticneurodevelopmentplacentaserotonin

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...