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Updated: May 9, 2026

Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
Vitamin D and skeletal growth and development
1Department of Pediatrics, Louisiana State University Health Sciences Center-Shreveport, 1501 King's Hwy, Shreveport, LA, 71103, USA, wkoo@lsuhsc.edu.
Optimizing vitamin D status is crucial for skeletal growth and maximizing peak bone mass, which is key to preventing osteoporosis. Research reviews data on 25-hydroxyvitamin D (25 OHD) levels and their impact on children
Area of Science:
- Pediatric Endocrinology
- Nutritional Science
- Bone Metabolism
Background:
- Vitamin D is essential for bone health and skeletal development.
- Optimizing vitamin D status is vital for achieving peak bone mass, crucial for osteoporosis prevention.
- There is ongoing debate regarding optimal vitamin D levels and deficiency thresholds.
Purpose of the Study:
- To review recent data on circulating 25-hydroxyvitamin D (25 OHD) concentrations.
- To examine the relationship between 25 OHD levels and skeletal growth in children.
- To investigate vitamin D status in both healthy children and those with deficiency.
Main Methods:
- Literature review of recent studies.
- Analysis of data on circulating 25-hydroxyvitamin D (25 OHD) levels.
- Examination of skeletal growth parameters in pediatric populations.
Main Results:
- Data on 25-hydroxyvitamin D (25 OHD) concentrations and skeletal growth were analyzed.
- The relationship between vitamin D status and skeletal development in children was investigated.
- Findings pertain to both healthy children and those with nutritional vitamin D deficiency.
Conclusions:
- Vitamin D status is critical for bone mineral metabolism and skeletal growth.
- Achieving optimal vitamin D levels may be key to maximizing peak bone mass.
- Further clarification is needed on defining healthy vitamin D status and deficiency thresholds.
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