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Updated: May 9, 2026

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

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Published on: May 7, 2020

Meningitis retention syndrome.

Abhishek Krishna¹, Pavan Devulapally, Ibrahim Ghobrial

¹Department of Internal Medicine, University of Pittsburgh Medical Centre-McKeesport Hospital, McKeesport, PA, USA.

Journal of Community Hospital Internal Medicine Perspectives

|July 25, 2013

Summary

This summary is machine-generated.

Meningitis Retention Syndrome (MRS), a rare complication of meningitis often caused by HSV-2, can lead to urinary retention. Early antiviral treatment in a patient with aseptic meningitis and HSV-2 showed a favorable outcome.

Keywords:

Elsberg syndrome acyclovir aseptic meningitis atonic bladder herpes simplex 2 virus infection polyradiculitis radiculomyelitis

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Area of Science:

Neurology
Infectious Diseases

Background:

Meningitis Retention Syndrome (MRS) is a rare complication of meningitis characterized by urinary retention.
It is most frequently associated with Herpes Simplex Virus type 2 (HSV-2) meningitis.

Observation:

A 50-year-old woman presented with meningitis symptoms, flu-like illness, and urinary retention.
Cerebrospinal fluid analysis revealed aseptic meningitis with HSV-2 detected by PCR.
Brain and spine MRIs were normal, but the patient exhibited atonic bladder causing significant urinary retention.

Findings:

The patient was diagnosed with Meningitis Retention Syndrome (MRS), a condition linked to meningitis and urinary retention.
This case highlights the association between HSV-2 meningitis and MRS, a poorly understood neurological complication.
MRS is distinguished from Elsberg syndrome, which involves lumbosacral polyradiculitis.

Implications:

Early diagnosis and prompt antiviral therapy are crucial for managing MRS and improving patient outcomes.
Further research is needed to elucidate the central pathway involvement in the pathogenesis of MRS.
This case underscores the importance of recognizing MRS as a potential complication in patients with meningitis, particularly HSV-2 meningitis.