Related Experiment Video
Updated: May 9, 2026

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
Published on: July 27, 2022
Nanoemulsion-based oral delivery systems for lipophilic bioactive components: nutraceuticals and pharmaceuticals
1Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA. mcclements@foodsci.umass.edu
Abstract:
Nanoemulsions have considerable potential for encapsulating, protecting and delivering lipophilic bioactive components via the oral route, such as pharmaceuticals (drugs) and nutraceuticals (food components with specific health benefits). These systems can be fabricated from generally recognized as safe ingredients using relatively simple processing operations, such as mixing and homogenization. Some of the potential advantages of nanoemulsions over conventional emulsions include higher bioaccessibility, higher physical stability and higher optical clarity. An overview of the current status of nanoemulsion fabrication, stability, properties and biological fate is given, with special emphasis on the suitability of nanoemulsions for the oral delivery of hydrophobic bioactive components, such as drugs and nutraceuticals.
Related Concept Videos
Oral Drug Delivery Systems: Introduction
Bioavailability Enhancement: Drug Permeability Enhancement
Oral Drug Delivery Systems: Delayed-Release Systems
Bioavailability Enhancement: Drug Solubility Enhancement
Factors Affecting Dissolution: Particle Size and Effective Surface Area
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
