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Urethral recurrence following radical cystectomy.
1Department of Urology, University of Tennessee Hospitals, Memphis.
The Journal of Urology
|September 1, 1990
Summary
Transitional cell carcinoma (TCC) in the prostate significantly increases urethral recurrence risk after radical cystoprostatectomy. Patients with prostatic TCC require rigorous screening and may benefit from prophylactic urethrectomy.
Area of Science:
- Urology
- Oncology
Background:
- Radical cystoprostatectomy is a treatment for bladder cancer.
- Urethral recurrence is a potential complication after this procedure.
Purpose of the Study:
- To identify risk factors for urethral recurrence after radical cystoprostatectomy.
- To assess the impact of prostatic involvement on urethral recurrence rates.
Main Methods:
- Retrospective review of 86 men undergoing radical cystoprostatectomy for transitional cell carcinoma of the bladder.
- Assessment of prostatic involvement, tumor extent in the bladder, and distal ureters.
Main Results:
- 11 of 30 patients (37%) with prostatic tumor involvement experienced urethral recurrence.
- Only 2 of 56 patients (4%) without prostatic involvement had recurrence.
- Prostatic involvement is a significant predictor of urethral recurrence.
Conclusions:
- Rigorous screening for prostate transitional cell carcinoma before cystectomy is recommended.
- Prophylactic urethrectomy should be considered for patients with prostatic involvement.
- Patients without prostatic involvement are at low risk for urethral recurrence.