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Integrated Compensatory Responses in a Human Model of Hemorrhage
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Published on: November 20, 2016

Evolution of biomedical research during combat operations.

Jennifer J Hatzfeld1, John D Childs, Michael P Dempsey

  • 1David Grant Medical Center, Travis Air Force Base, California, USA. jennifer.hatzfeld@gmail.com

The Journal of Trauma and Acute Care Surgery
|July 26, 2013
PubMed
Summary

Conducting biomedical research in combat zones presents unique challenges, including protocol approval and informed consent in austere environments. Lessons learned emphasize clear procedures and anticipating wartime complexities for successful military medical research.

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Area of Science:

  • Military Medicine
  • Trauma Research
  • Biomedical Research

Background:

  • Human research protection programs and combat casualty research teams enable complex studies in combat zones.
  • Research in these environments faces significant, unique challenges.

Purpose of the Study:

  • To describe the development and conduct of three trauma-related biomedical research studies in Afghanistan.
  • To highlight challenges and lessons learned from conducting research in a combat environment.

Main Methods:

  • Development and execution of three prospective, multisite, trauma-related biomedical research studies.
  • Analysis of challenges encountered during in-theater research.

Main Results:

  • Key challenges include in-theater protocol approval, informed consent, and logistical hurdles in austere settings.
  • Lessons learned include the need for clear operating procedures, selective data collection, and anticipating the "fog and friction" of war.

Conclusions:

  • Biomedical research in combat zones is crucial for military medicine but inherently difficult.
  • This study informs future research design and conduct in theaters of war, enhancing research capabilities.